Intra-articular pressure in rheumatoid arthritis of the knee. I. Pressure changes during passive joint distension.

نویسندگان

  • M I Jayson
  • A J St Dixon
چکیده

In any compartment with stiff walls the excess pressure of fluid within is determined by a combination of the volume of fluid and the elasticity of the walls. The elastance of the space as a whole can be represented as a change in pressure for unit change in volume (dP/dV or mm. Hg/ml.). It follows that within the knee joint higher pressures will develop in the presence of effusions and when the elasticity of the joint capsule is increased. Thce intra-articular pressure, that is the pressure in the synovial fluid (not that between the contact areas of the articulating surfaces), has been determined in the resting, passively distended knees of rheumatoid and control subjects with various volumes of simulated effusion.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Histopathological changes of the antigen-induced chronic arthritis in the knee joint of the rabbit

Background and Objectives: The cause and pathophysiology of rheumatoid arthritis has not been fully understood and an experimental model of this disease is essential for research on the problem. In this research study, establishment and histopathological changes of chronic arthritis due to intra-articula...

متن کامل

Histological assessment of intera articular injection of 90Y- hydroxyapatite radiocolloid in enrofloxacin induced rheumatoid arthritis in rat models

Histological assessment of intera articular injection of 90Y- hydroxyapatite radiocolloid in enrofloxacin induced rheumatoid arthritis in rat models   Introduction: Rheumatoid arthritis (RA) is one of the most common and disabling diseases in societies that causes chronic synovial inflammation and joint damages. Several pharmaceutical and non-pharmaceutical treatments of RA have been developed...

متن کامل

Direct assessment of synovial blood flow and its relation to induced hydrostatic pressure changes.

A method for measuring synovial blood flow changes using the laser Doppler technique is described. Mean blood flow and mean pulse amplitude decreased by 50-70% in relation to the reference level when the intra-articular hydrostatic pressure in effusive knee joints of patients with rheumatoid arthritis was increased. As an increase of intra-articular pressure of as little as 20 mmHg decreased sy...

متن کامل

The Effect of Intra-Articular Injection of Two Anti TNF Drugs on Histopathology and Effect of Local Infusion of these Drugs on Blood Flow of Chronically Inflamed Joints in Rabbit

Background & Aims: The anti TNF drugs are new line treatment for articular inflammatory diseases which are used systemically, but due to expensiveness and some systemic adverse effects have limited usage. The aims of this study were to investigate the effect of intra-articular (local) injection of Etanercept and Infliximab as two anti TNF drugs on histopathology and also due to the important ro...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 29 3  شماره 

صفحات  -

تاریخ انتشار 1970